Let's say that Paramount has just had an epiphany and realized that you are the sole individual who can re-energize the Star Trek license by taking a page from Battlestar Galactica and Marvel Comics' Ultimate line and put together a whole new Star Trek series set in the original series time but updated and reimagined to reflect today's atmosphere and times. You have no restrictions on budget and can cast anyone. My cast would probably include:

Captain James T. Kirk - Brendan Fraser
Science Officer Spock - Christopher Walken
Chief Medical Officer Leonard "Bones" McCoy - Kelsey Grammar
Chief Engineer Montgomery Scott - Jude Law
Lieutenant Hikaru Sulu - Gary Dourdan (Warrick from [i]CSI[/i])
Ensign Pavel Chekov - George Eads (Stokes from [i]CSI[/i])
Lieutenant Commander Uhura - Angelina Joile
Yeoman Janice Rand - Tricia Helfer (Number Six from [i]Battlestar Galactica[/i])
Nurse Christine Chapel - Marg Helgenberger

Who would you choose?